Article
Leveraging a Multi-Omics Strategy for Prioritizing Personalized Candidate Mutation-Driver Genes: A Proof-of-Concept Study.
Scientific reports - 3 Dec 2015
Ding Keyue, Wu Songfeng, Ying Wantao, Pan Qi, Li Xiaoyuan, Zhao Dachun, Li Xianyu, Zhao Qing, Zhu Yunping, Ren Hong, Qian Xiaohong
Abstract excerpt
The expression of mutant forms of proteins (e.g., oncogenes and tumor suppressors) has implications in cancer biology and clinical practice. Initial efforts have been made to characterize the transcription of tumor-mutated alleles; however, few studies have been reported to link tumor-mutated alleles to proteomics. We aimed to characterize the transcriptional and translational patterns of tumor-mutated alleles....
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