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Article

Mutational spectrum of intraepithelial neoplasia in pancreatic heterotopia.

Human pathology - 1 Feb 2016

Ma Changqing, Gocke Christopher D, Hruban Ralph H, Belchis Deborah A

Abstract excerpt

Heterotopic pancreatic parenchyma recapitulates the normal pancreas in extrapancreatic locations and, on rare occasions, can even give rise to pancreatic adenocarcinoma. The genetic signatures of pancreatic adenocarcinoma and its precursor lesions are well characterized. We explored the genetic alterations in precursor lesions (intraductal papillary mucinous neoplasms [IPMN], pancreatic intraepithelial neoplasia...

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Topics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26626780
DOI: 10.1016/j.humpath.2015.09.023
PMCID: PMC4715935

Genes

KRAS
BRAF
GNAS
SMAD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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