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Article

Molecular heterogeneity and commonalities in pancreatic cancer precursors with gastric and intestinal phenotype.

Gut - 1 Mar 2023

Liffers Sven-Thorsten, Godfrey Laura, Frohn Lisa, Haeberle Lena, Yavas Aslihan, Vesce Rita, Goering Wolfgang, Opitz Friederike V, Stoecklein Nickolas, Knoefel Wolfram Trudo, Schlitter Anna Melissa, Klöppel Guenter, Espinet Elisa, Trumpp Andreas, Siveke Jens T, Esposito Irene

Abstract excerpt

OBJECTIVE: Due to the limited number of modifiable risk factors, secondary prevention strategies based on early diagnosis represent the preferred route to improve the prognosis of pancreatic ductal adenocarcinoma (PDAC). Here, we provide a comparative morphogenetic analysis of PDAC precursors aiming at dissecting the process of carcinogenesis and tackling the heterogeneity of preinvasive lesions. DESIGN: Targeted...

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Share to Carcinoma, Pancreatic Ductal
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35944927
DOI: 10.1136/gutjnl-2021-326550
PMCID: PMC9933174

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