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Article

Molecular genetics of pancreatic intraepithelial neoplasia.

Journal of hepato-biliary-pancreatic surgery - 1 Jan 2007

Feldmann Georg, Beaty Robert, Hruban Ralph H, Maitra Anirban

Abstract excerpt

BACKGROUND: Recent evidence suggests that noninvasive precursor lesions, classified as pancreatic intraepithelial neoplasia (PanIN), can progress to invasive pancreatic cancer. This review will discuss the major genetic alterations in PanIN lesions. METHODS: A comprehensive review of the literature was performed in order to find studies on the molecular profile of human PanIN lesions. In addition, recent...

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Source

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Identifiers

PMID: 17520196
DOI: 10.1007/s00534-006-1166-5
PMCID: PMC2666331

Genes

BRCA2
SMAD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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