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Rod-genesis driven by <i>mafba</i> in an <i>nrl</i> knockout zebrafish model with altered photoreceptor compositions and progressive retinal degeneration

2021-09-30

Abstract excerpt

The neural retina leucine zipper ( NRL ) is an essential gene for the fate determination and differentiation of rod photoreceptors in mammals. Mutations in NRL have been associated with autosomal recessive enhanced S-cone syndrome and autosomal dominant retinitis pigmentosa. However, the exact role of Nrl in regulating the development and maintenance of photoreceptors in zebrafish, a popular animal model used fo...

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Literature Corpus work
53b5fab2-0dbb-5c6b-a0fa-0e6a226517df
DOI
10.1101/2021.09.29.462301
Open publication

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Rod-genesis driven by <i>mafba</i> in an <i>nrl</i> knockout zebrafish model with altered photoreceptor compositions and progressive retinal degenerationDOI 10.1101/2021.09.29.462301
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