Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A critical role of CaBP4 in the cone synapse.

Investigative ophthalmology & visual science - 1 Nov 2005

Maeda Tadao, Lem Janis, Palczewski Krzysztof, Haeseleer Françoise

Abstract excerpt

PURPOSE: CaBP4, a photoreceptor-specific protein of the rods and cones, is essential for the development and maintenance of the mouse photoreceptor synapse. In this study, double CaBP4/rod alpha-transducin knockout (Cabp4(-/-)Gnat1(-/-)) mice lacking the rod-mediated component of electrophysiologic responses were generated and analyzed to investigate the role of CaBP4 in cones. METHODS: The retinal morphology and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Photic Stimulation
Share to Electroretinography
Share to Fluorescent Antibody Technique, Indirect

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Retinal Cone Photoreceptor Cells

Share to Retinal Rod Photoreceptor Cells

Share to Synaptic Transmission

Share to Transducin

Share to Vision, Ocular

Source

Open in PubMed Open full text

Identifiers

PMID: 16249514
DOI: 10.1167/iovs.05-0478
PMCID: PMC1351246

Genes

ERG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A critical role of CaBP4 in the cone synapse.PMID 16249514Read ↗

Validating Fluorescent Chrnb4.EGFP Mouse Models for the Study of Cone Photoreceptor DegenerationSemantic proximity Read ↗

Diminished Cone Sensitivity in cpfl3 Mice Is Caused by Defective Transducin Signaling.Semantic proximity Read ↗

Rod-cone dystrophy in an adult with GNB1-related disorder: An expansion of the phenotype and natural history.Semantic proximity Read ↗

Visual Cone Arrestin 4 Contributes to Visual Function and Cone Health.Semantic proximity Read ↗

Cone photoreceptor function loss-3, a novel mouse model of achromatopsia due to a mutation in Gnat2.Semantic proximity Read ↗

A naturally occurring mouse model of achromatopsia: characterization of the mutation in cone transducin and subsequent retinal phenotype.Semantic proximity Read ↗

Structural and functional abnormalities of retinal ribbon synapses due to Cacna2d4 mutation.Semantic proximity Read ↗

Retinal network dysfunction precedes structural degeneration in severe <i>GUCA1A</i> cone-rod dystrophySemantic proximity Read ↗

Impaired cone function and cone degeneration resulting from CNGB3 deficiency: down-regulation of CNGA3 biosynthesis as a potential mechanism.Semantic proximity Read ↗

Arrestin 1 and Cone Arrestin 4 Have Unique Roles in Visual Function in an All-Cone Mouse Retina.Semantic proximity Read ↗

Therapeutic restoration of synaptic architecture, retinal and visual function, and prevention of retinal degeneration in a mouse model of retinal dystrophySemantic proximity Read ↗

Activation of rod input in a model of retinal degeneration reverses retinal remodeling and induces formation of normal synapses, circuitry and visual signaling in the adult retinaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.