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Article

Within patient microevolution of Mycobacterium tuberculosis correlates with heterogeneous responses to treatment.

Scientific reports - 1 Dec 2015

Liu Qingyun, Via Laura E, Luo Tao, Liang Lili, Liu Xin, Wu Sufang, Shen Qingyu, Wei Wang, Ruan Xianglin, Yuan Xing, Zhang Guolong, Barry Clifton E, Gao Qian

Abstract excerpt

Genetic heterogeneity of Mycobacterium tuberculosis (MTB) within a patient has caused great concern as it might complicate antibiotic treatment and cause treatment failure. But the extent of genetic heterogeneity has not been described in detail nor has its association with heterogeneous treatment response. During treatment of a subject with MDR-TB, serial computed tomography (CT) scans showed this subject had...

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Identifiers

PMID: 26620446
DOI: 10.1038/srep17507
PMCID: PMC4664930

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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