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Article

Genetic Associations of Alexithymia in Predicting Interferon-Induced Depression in Chronic Hepatitis C.

Psychopathology - 1 Jan 2015

Porcelli Piero, Cozzolongo Raffaele, Cariola Filomena, Giannuzzi Vito, Lanzilotta Elsa, Gentile Mattia, Sonnante Gabriella, Leandro Gioacchino

Abstract excerpt

BACKGROUND: Previous studies have shown that alexithymia is associated with gene polymorphisms that regulate the availability of serotonin (5-HT) in the brain. Since the 5-HT network is involved in interferon (IFN)-induced depression, this paper aimed to investigate the role of alexithymia and the functional gene variants of the 5-HT1A receptor (HTR1A) and the 5-HT transporter (5-HTTLPR) in induction of...

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Source

Identifiers

PMID: 26609890
DOI: 10.1159/000441682

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic Associations of Alexithymia in Predicting Interferon-Induced Depression in Chronic Hepatitis C.PMID 26609890Read ↗

Serotonin-1A receptor CC genotype is associated with persistent depression related to interferon-alpha in hepatitis C patients.Semantic proximity Read ↗

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Serotonin gene polymorphisms and lifetime mood disorders in predicting interferon-induced depression in chronic hepatitis C.Semantic proximity Read ↗

Analysis of functional variants reveals new candidate genes associated with alexithymia.Semantic proximity Read ↗

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