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Article

Association between the catechol O-methyltransferase Val108/158Met polymorphism and alexithymia.

Neuropsychobiology - 1 Jan 2005

Ham Byung-Joo, Lee Min-Soo, Lee Young-Mee, Kim Meyoung-Kon, Choi Myoung-Jin, Oh Kang-Seob, Jung Han Yong, Lyoo In Kyoon, Choi Ihn-Geun

Abstract excerpt

It has been suggested that the characteristics of alexithymia result from deficits in frontal lobe functioning, and the prefrontal cortex is particularly dependent on the catechol O-methyltransferase (COMT) pathway. We investigated the relationship between COMT Val108/158Met, serotonin transporter coding sequence (5-HT transporter gene-linked polymorphic region; 5-HTTLPR) polymorphisms, and alexithymia. The study...

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Source

Identifiers

PMID: 16127282
DOI: 10.1159/000087846

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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