Article
Nonparametric Risk and Nonparametric Odds in Quantitative Genetic Association Studies.
Scientific reports - 15 Jul 2015
Zhang Wei, Li Qizhai
Abstract excerpt
The coefficient in a linear regression model is commonly employed to evaluate the genetic effect of a single nucleotide polymorphism associated with a quantitative trait under the assumption that the trait value follows a normal distribution or is appropriately normally distributed after a certain transformation. When this assumption is violated, the distribution-free tests are preferred. In this work, we propose...
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