Article
Functional polymorphisms in the IL6 gene promoter and the risk of urinary bladder cancer in India.
Cytokine - 1 Jan 2016
Gautam Kirti Amresh, Muktanand Tripathi, Sankhwar Satya Narayan, Goel Apul, Sankhwar Pushp Lata, Rajender Singh
Abstract excerpt
BACKGROUND: Interleukin-6 is a multifunctional cytokine, which plays a key role in tumor proliferation and differentiation. Variations in its gene (IL6) sequence may affect the risk of developing various cancers, including urinary bladder cancer. The present study was done to find the association of functional polymorphisms in the IL6 promoter with urinary bladder cancer. MATERIALS AND METHODS: Single nucleotide...
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