Article
An Interleukin-6 Single Nucleotide Polymorphism and Susceptibility to Prostate Adenocarcinoma and Bone Metastasis in an Iranian Population
Asian Pacific journal of cancer prevention : APJCP - 25 Jun 2018
Dargahi Abbasabad Ghader, Banan Khojasteh Seyed Mahdi, Eskandari Naji Hadi, Zamani Mohammad Reza, Hajipour Hamed, Serati-Nouri Hamed
Abstract excerpt
Objective: Interleukin-6 (IL-6) is an inflammatory cytokine shown to be a strong factor for growth, proliferation and metastasis with many malignancies. The promoter single nucleotide polymorphism (SNPs) -174G>C (rs1800795) can alter the transcriptional pattern of this gene. The present study was aimed at assessing effects of the IL-6 (rs1800795) SNP on risk of benign prostate hyperplasia (BPH) and prostatic...
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