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Meta-analysis of the role of IL-6 rs1800795 polymorphism in the susceptibility to prostate cancer: Evidence based on 17 studies.

Medicine - 1 Mar 2017

Liu Tong-Zu, Guo Zhong-Qiang, Wang Ting, Cao Yue, Huang Di, Wang Xing-Huan

Abstract excerpt

Playing critical roles in immune responses, interleukin-6 (IL-6) has been proposed to be involved in the development of multiple cancers, including prostate cancer. The rs1800795 polymorphism in the promoter of the gene IL-6 can affect the transcription and expression of the gene, becoming a common target in association studies on tumors. We therefore carried out this meta-analysis to further discuss the...

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PMID: 28296724
DOI: 10.1097/MD.0000000000006126
PMCID: PMC5369879

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