Article
Interleukins-6 -174G/C (rs1800795) and -572C/G (rs1800796) polymorphisms and prostate cancer risk.
Molecular immunology - 1 Dec 2023
Iqbal Muhammad Sarfaraz, Peng Kaoqing, Sardar Nimra, Iqbal Muhammad Hasnain, Ghani Muhammad Usman, Tanvir Fouzia, Gu Di, Guohua Zeng, Duan Xiaolu
Abstract excerpt
Prostate cancer (PCa) is an aggressive cancer influenced by a complex interplay of genetic and environmental factors. Amongst these risk factors, the impact of Interleukin6 (IL6) gene polymorphisms in PCa risk has received a lot of attention. IL-6 is a cytokine that has been implicated in the pathogenesis of several malignancies, including PCa. Two IL-6 gene polymorphisms, - 174 G/C (rs1800795) and - 572 C/G...
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