Article
Interleukin-12 and interleukin-6 gene polymorphisms and risk of bladder cancer in the Iranian population.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2014
Ebadi Nader, Jahed Marzieh, Mivehchi Mohamad, Majidizadeh Tayebeh, Asgary Mojgan, Hosseini Seyed Ali
Abstract excerpt
Interleukin-12 (IL-12) as an antitumor and interleukin-6 (IL-6) as an inflammatory cytokine, are immunomodulatory products that play important roles in responses in cancers and inflammation. We tested the association between two polymorphisms of IL-12(1188A>C; rs3212227) and IL-6 (-174 C>G) and the risk of bladder cancer in 261 patients and 251 healthy individuals. We also investigated the possible association of...
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