Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IL-6 -174G>C polymorphism and cancer risk: a meta-analysis involving 29,377 cases and 37,739 controls.

Molecular biology reports - 1 Apr 2011

Xu Bin, Niu Xiao-Bing, Wang Zi-Dun, Cheng Wei, Tong Na, Mi Yuan-Yuan, Min Zhi-Chao, Tao Jun, Li Peng-Chao, Zhang Wei, Wu Hong-Fei, Zhang Zheng-Dong, Wang Zeng-Jun, Hua Li-Xin, Feng Ning-Han, Wang Xin-Ru

Abstract excerpt

Interleukin-6 (IL-6) is a multifunctional cytokine involved in different physiologic and pathophysiologic processes and plays important roles in the etiology of cancer. The -174G>C polymorphism of the IL-6 gene influences IL-6 transcription and has been implicated in cancer risk. However, published data have been conflicting. To derive a more precise estimation of the relationship, a meta-analysis of 29,377...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to Black People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Interleukin-6

Share to Neoplasms

Share to Odds Ratio

Share to Polymorphism, Single Nucleotide

Share to White People

Source

Identifiers

PMID: 21104146
DOI: 10.1007/s11033-010-0399-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IL-6 -174G>C polymorphism and cancer risk: a meta-analysis involving 29,377 cases and 37,739 controls.PMID 21104146Read ↗

Association of the IL6 polymorphism rs1800796 with cancer risk: a meta-analysis.Semantic proximity Read ↗

Association of the interleukin-6 gene -572G/C polymorphism with cancer risk: a meta-analysis.Semantic proximity Read ↗

Associations of interleukin-6 gene polymorphisms with cancer risk: Evidence based on 49,408 cancer cases and 61,790 controls.Semantic proximity Read ↗

Association of IL-6 -174G>C (rs1800795) polymorphism with cervical cancer susceptibility.Semantic proximity Read ↗

Statistical meta-analysis to investigate the association between the Interleukin-6 (IL-6) gene polymorphisms and cancer risk.Semantic proximity Read ↗

Functional polymorphisms in the IL6 gene promoter and the risk of urinary bladder cancer in India.Semantic proximity Read ↗

Association between the interleukin-6 gene polymorphisms and renal cancer risk.Semantic proximity Read ↗

Interleukin-6-174G>C gene promoter polymorphism and prognosis in patients with cancer.Semantic proximity Read ↗

The interleukin-6 -174G/C polymorphism and prostate cancer risk: a systematic review and meta-analysis.Semantic proximity Read ↗

Association of IL-6 -174 G>C Polymorphism with Susceptibility to Colorectal Cancer and Gastric Cancer: a Systematic Review and Meta-Analysis.Semantic proximity Read ↗

Meta-analysis of the role of IL-6 rs1800795 polymorphism in the susceptibility to prostate cancer: Evidence based on 17 studies.Semantic proximity Read ↗

Interleukin-6 gene -174G>C and -636G>C promoter polymorphisms and prostate cancer risk.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.