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Article

Automated Classification and Cluster Visualization of Genotypes Derived from High Resolution Melt Curves.

PloS one - 1 Jan 2015

Kanderian Sami, Jiang Lingxia, Knight Ivor

Abstract excerpt

INTRODUCTION: High Resolution Melting (HRM) following PCR has been used to identify DNA genotypes. Fluorescent dyes bounded to double strand DNA lose their fluorescence with increasing temperature, yielding different signatures for different genotypes. Recent software tools have been made available to aid in the distinction of different genotypes, but they are not fully automated, used only for research purposes,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26605797
DOI: 10.1371/journal.pone.0143295
PMCID: PMC4659556

Genes

MTHFR
VKORC1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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