Article
Comparison of Survival Outcomes According to BRCA1/2 Variant Type in High-grade Serous Ovarian Cancer.
In vivo (Athens, Greece) - 1 Jan 2000
Lee Juhun, Kim Jong Mi, Lee Yoon Hee, Chong Gun Oh, Lee Nan Young, Lee In Hee, Park Ji Young, Hong Dae Gy
Abstract excerpt
BACKGROUND/AIM: Mutations of BRCA1/2 improve cancer prognosis due to their better response to platinum-based chemotherapy. This study evaluated overall survival (OS) and progression-free survival (PFS) under similar conditions of first-line adjuvant chemotherapy within seven years in high-grade serous ovarian cancer (HGSOC). PATIENTS AND METHODS: A total of 160 patients were enrolled. The pathogenic BRCA1/2...
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