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The Mutational Landscape of Early-Onset Breast Cancer: A Next-Generation Sequencing Analysis

21 Jan 2022

Abstract excerpt

BACKGROUND: Around 5%-7% of breast cancer cases are diagnosed in women younger than 40, making it the leading cause of female cancer in the 25- to 39-year-old age group. Unfortunately, young age at diagnosis is linked to a more aggressive tumor biology and a worse clinical outcome. The identification of the mutational landscape of breast cancer in this age group could optimize the management. METHODS: We...

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PMID: 35127508
DOI: 10.3389/fonc.2021.797505

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