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Article

Molecular characterization of serous ovarian carcinoma using a multigene next generation sequencing cancer panel approach.

BMC research notes - 17 Nov 2014

Ab Mutalib Nurul-Syakima, Syafruddin Saiful Effendi, Md Zain Reena Rahayu, Mohd Dali Ahmad Zailani Hatta, Mohd Yunos Ryia Illani, Saidin Sazuita, Jamal Rahman, Mokhtar Norfilza M

Abstract excerpt

BACKGROUND: High grade serous ovarian cancer is one of the poorly characterized malignancies. This study aimed to elucidate the mutational events in Malaysian patients with high grade serous ovarian cancer by performing targeted sequencing on 50 cancer hotspot genes. RESULTS: Nine high grade serous ovarian carcinoma samples and ten normal ovarian tissues were obtained from Universiti Kebangsaan Malaysia Medical...

Read the complete abstract on PubMed

Topics

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Share to Carcinoma, Ovarian Epithelial
Share to Cystadenocarcinoma, Serous

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Databases, Genetic

Share to High-Throughput Nucleotide Sequencing

Share to Neoplasm Grading

Share to Neoplasms, Glandular and Epithelial

Share to Ovarian Neoplasms

Share to Tumor Suppressor Protein p53

Source

Open in PubMed Open full text

Identifiers

PMID: 25404506
DOI: 10.1186/1756-0500-7-805
PMCID: PMC4242548

Genes

APC
EGFR
FGFR3
KDR
KIT
MET
PDGFRA
RET
SMO
STK11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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