Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prevalence of germline TP53 variants among early-onset breast cancer patients from Polish population.

Breast cancer (Tokyo, Japan) - 1 Jan 2021

Rogoża-Janiszewska Emilia, Malińska Karolina, Górski Bohdan, Scott Rodney J, Cybulski Cezary, Kluźniak Wojciech, Lener Marcin, Jakubowska Anna, Gronwald Jacek, Huzarski Tomasz, Lubiński Jan, Dębniak Tadeusz

Abstract excerpt

BACKGROUND: The objective of this study was to determine spectrum and prevalence of germline mutations in TP53 gene among Polish women with early-onset breast cancer (BC), which has not been determined until now. METHODS: A cohort of 100 females with BC diagnosed ≤ 30 years of age and with a positive family history of cancer was used as a discovery cohort. 1880 women with BC ≤ 45 years old and a control group of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cohort Studies

Share to Germ-Line Mutation

Share to Heterozygote

Share to Poland

Share to Prevalence

Share to Tumor Suppressor Protein p53

Source

Open in PubMed Open full text

Identifiers

PMID: 32888145
DOI: 10.1007/s12282-020-01151-7
PMCID: PMC7796867

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prevalence of germline TP53 variants among early-onset breast cancer patients from Polish population.PMID 32888145Read ↗

Prevalence of germline mutations in the TP53 gene in patients with early-onset breast cancer in the Mexican populationSemantic proximity Read ↗

Prevalence and clinical impact of TP53 germline mutations in Chinese women with breast cancerSemantic proximity Read ↗

TP53 germline mutation testing in early-onset breast cancer: findings from a nationwide cohortSemantic proximity Read ↗

Breast Cancer Phenotype Associated With Li-Fraumeni Syndrome: A Brazilian Cohort Enriched by TP53 p.R337H CarriersSemantic proximity Read ↗

Phenotype analysis of families with TP53 germline variants at the Center for Familial Breast and Ovarian Cancer, Cologne.Semantic proximity Read ↗

Population-based estimate of the contribution of TP53 mutations to subgroups of early-onset breast cancer: Australian Breast Cancer Family Study.Semantic proximity Read ↗

Comparable frequency of BRCA1, BRCA2 and TP53 germline mutations in a multi-ethnic Asian cohort suggests TP53 screening should be offered together with BRCA1/2 screening to early-onset breast cancer patients.Semantic proximity Read ↗

Mutation Spectra of BRCA Genes in Iranian Women with Early Onset Breast Cancer - 15 Years Experience.Semantic proximity Read ↗

Germline Mutation Analysis in Sporadic Breast Cancer Cases with Clinical CorrelationsSemantic proximity Read ↗

Clinical implications of germline mutations in breast cancer: TP53.Semantic proximity Read ↗

Novel mutations in the BRCA1 and BRCA2 genes in Iranian women with early-onset breast cancer.Semantic proximity Read ↗

Prediction of pathogenic mutations in patients with early-onset breast cancer by family history.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.