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Article

MUC5B and Idiopathic Pulmonary Fibrosis.

Annals of the American Thoracic Society - 1 Nov 2015

Yang Ivana V, Fingerlin Tasha E, Evans Christopher M, Schwarz Marvin I, Schwartz David A

Abstract excerpt

Idiopathic pulmonary fibrosis (IPF), a fatal disease that is a result of complex interactions between genetics and the environment, has limited treatment options. We have identified the MUC5B promoter polymorphism and other common genetic variants that in aggregate explain roughly one-third of disease risk. The MUC5B promoter polymorphism is the strongest and the most replicated genetic risk factor for IPF,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Share to Medical Imaging and Pathology Studies

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Share to Promoter Regions, Genetic

Source

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Identifiers

PMID: 26595739
DOI: 10.1513/AnnalsATS.201503-110AW
PMCID: PMC4722833

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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