Genetics and Genomics of Pulmonary Fibrosis: Charting the Molecular Landscape and Shaping Precision Medicine.

doi:10.1164/rccm.202401-0238SO

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Genetics and Genomics of Pulmonary Fibrosis: Charting the Molecular Landscape and Shaping Precision Medicine.

American journal of respiratory and critical care medicine - 15 Aug 2024

Adegunsoye Ayodeji, Kropski Jonathan A, Behr Juergen, Blackwell Timothy S, Corte Tamera J, Cottin Vincent, Glanville Allan R, Glassberg Marilyn K, Griese Matthias, Hunninghake Gary M, Johannson Kerri A, Keane Michael P, Kim John S, Kolb Martin, Maher Toby M, Oldham Justin M, Podolanczuk Anna J, Rosas Ivan O, Martinez Fernando J, Noth Imre, Schwartz David A

Abstract excerpt

Recent genetic and genomic advancements have elucidated the complex etiology of idiopathic pulmonary fibrosis (IPF) and other progressive fibrotic interstitial lung diseases (ILDs), emphasizing the contribution of heritable factors. This state-of-the-art review synthesizes evidence on significant genetic contributors to pulmonary fibrosis (PF), including rare genetic variants and common SNPs. The MUC5B promoter...

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Identifiers

PMID: 38573068
DOI: 10.1164/rccm.202401-0238SO
PMCID: PMC11351799

Genes

MUC5B
SFTPC
TERT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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