Article
Focused molecular analysis of small cell lung cancer: feasibility in routine clinical practice.
BMC research notes - 18 Nov 2015
Abdelraouf Fatma, Sharp Adam, Maurya Manisha, Mair Debbie, Wotherspoon Andrew, Leary Alex, Gonzalez de Castro David, Bhosle Jaishree, Nassef Ayatallah, Gaafar Taghrid, Popat Sanjay, Yap Timothy A, O'Brien Mary
Abstract excerpt
BACKGROUND: There is an urgent need to identify molecular signatures in small cell lung cancer (SCLC) that may select patients who are likely to respond to molecularly targeted therapies. In this study, we investigate the feasibility of undertaking focused molecular analyses on routine diagnostic biopsies in patients with SCLC. METHODS: A series of histopathologically confirmed formalin-fixed, paraffin-embedded...
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