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Article

Characterization of fibroblast growth factor receptor 1 in small-cell lung cancer.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Apr 2014

Thomas Anish, Lee Jih-Hsiang, Abdullaev Zied, Park Kang-Seo, Pineda Marbin, Saidkhodjaeva Lola, Miettinen Markku, Wang Yisong, Pack Svetlana D, Giaccone Giuseppe

Abstract excerpt

INTRODUCTION: There remains a significant therapeutic need for small-cell lung cancer (SCLC). We and others have reported high frequency of copy number gains in cytogenetic bands encoding fibroblast growth factor receptor 1 (FGFR1) in SCLC tumors and cell lines. METHODS: Thirteen SCLC cell lines and 68 SCLC patient tumor samples were studied for FGFR1 amplification. Growth inhibition assays were performed using...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptor, Fibroblast Growth Factor, Type 1

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Source

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Identifiers

PMID: 24736083
DOI: 10.1097/JTO.0000000000000089
PMCID: PMC5705182

Genes

FGFR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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