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Article

Fibroblast Growth Factor Receptor 1 and Related Ligands in Small-Cell Lung Cancer

28 May 2015

Abstract excerpt

INTRODUCTION: Small-cell lung cancer (SCLC) accounts for 15% of all lung cancers and has been understudied for novel therapies. Signaling through fibroblast growth factors (FGF2, FGF9) and their high-affinity receptor has recently emerged as a contributing factor in the pathogenesis and progression of non-small-cell lung cancer. In this study, we evaluated fibroblast growth factor receptor 1 (FGFR1) and ligand...

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PMID: 26020126
DOI: 10.1097/jto.0000000000000562

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