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Article

EGFR mutation testing in pulmonary adenocarcinoma: evaluation of tumor cell number and tumor percent in paraffin sections of 120 small biopsies.

Lung cancer (Amsterdam, Netherlands) - 1 Jan 2015

Scarpino Stefania, Pulcini Federica, Di Napoli Arianna, Giubettini Maria, Ruco Luigi

Abstract excerpt

OBJECTIVES: Successful evaluation of EGFR mutational status in small biopsies may be hampered by the number of tumor cells present in the tissue section. The aim of the present study was to determine the minimal number of tumor cells necessary for a reliable EGFR mutation testing in lung adenocarcinoma. MATERIALS AND METHODS: The minimal number of tumor cells was determined experimentally in surgical specimens of...

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Source

Identifiers

PMID: 25468201
DOI: 10.1016/j.lungcan.2014.10.012

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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