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Article

Maturation status of sarcomere structure and function in human iPSC-derived cardiac myocytes.

Biochimica et biophysica acta - 1 Jul 2016

Bedada Fikru B, Wheelwright Matthew, Metzger Joseph M

Abstract excerpt

Human heart failure due to myocardial infarction is a major health concern. The paucity of organs for transplantation limits curative approaches for the diseased and failing adult heart. Human induced pluripotent stem cell-derived cardiac myocytes (hiPSC-CMs) have the potential to provide a long-term, viable, regenerative-medicine alternative. Significant progress has been made with regard to efficient cardiac...

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Identifiers

PMID: 26578113
DOI: 10.1016/j.bbamcr.2015.11.005
PMCID: PMC4864165

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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