Article

Induced Pluripotent Stem Cells Technology and Cardiomyocyte Generation: Progress, Uncertainties and Challenges in the Biological Features and Clinical Applications

2018-03-15

Abstract excerpt

Human induced pluripotent stem cells (hiPSCs) are reprogrammed cells that have hallmarks similar to embryonic stem cells including the capacity of self-renewal and differentiation into cardiac myocytes. The improvements in reprogramming and differentiating methods achieved in the past 10 years widened the use of hiPSCs, especially in cardiac research. hiPSC-derived cardiac myocytes (CMs) recapitulate phenotypic di...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7fcb8ede-ac23-5068-a002-b0dc0db2aacb
DOI: 10.20944/preprints201803.0115.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Induced Pluripotent Stem Cells Technology and Cardiomyocyte Generation: Progress, Uncertainties and Challenges in the Biological Features and Clinical ApplicationsDOI 10.20944/preprints201803.0115.v1Read

Induced pluripotent stem-cell-derived cardiomyocytes: cardiac applications, opportunities, and challenges.Semantic proximity Read

Human pluripotent stem cell-derived cardiomyocytes for heart regeneration, drug discovery and disease modeling: from the genetic, epigenetic, and tissue modeling perspectivesSemantic proximity Read

Concise Review: Cardiac Disease Modeling Using Induced Pluripotent Stem CellsSemantic proximity Read

Induced pluripotent stem cells in the inherited cardiomyopathies: From disease mechanisms to novel therapies.Semantic proximity Read

The march of pluripotent stem cells in cardiovascular regenerative medicineSemantic proximity Read

Comparative analysis of the cardiomyocyte differentiation potential of induced pluripotent stem cells reprogrammed from human atrial or ventricular fibroblastsSemantic proximity Read

Recent advances in regulating the proliferation or maturation of human-induced pluripotent stem cell-derived cardiomyocytesSemantic proximity Read

Stem Cell Technology in Cardiac Regeneration: A Pluripotent Stem Cell PromiseSemantic proximity Read

Current status of induced pluripotent stem cells in cardiac tissue regeneration and engineeringSemantic proximity Read

Embryonic stem cells and cardiomyocyte differentiation: phenotypic and molecular analyses.Semantic proximity Read

A Concise Review on Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Personalized Regenerative MedicineSemantic proximity Read

Cardiac Regeneration with Human Pluripotent Stem Cell-Derived CardiomyocytesSemantic proximity Read