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Concise Review: Maturation Phases of Human Pluripotent Stem Cell-Derived Cardiomyocytes

25 Jan 2013

Abstract excerpt

Human pluripotent stem cell-derived cardiomyocytes (hPS-CM) may offer a number of advantages over previous cardiac models, however, questions of their immaturity complicate their adoption as a new in vitro model. hPS-CM differ from adult cardiomyocytes with respect to structure, proliferation, metabolism and electrophysiology, better approximating fetal cardiomyocytes. Time in culture appears to significantly...

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PMID: 23355363
DOI: 10.1002/stem.1331

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