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Article

Shared Genetic Signals of Hypoxia Adaptation in Drosophila and in High-Altitude Human Populations.

Molecular biology and evolution - 1 Feb 2016

Jha Aashish R, Zhou Dan, Brown Christopher D, Kreitman Martin, Haddad Gabriel G, White Kevin P

Abstract excerpt

The ability to withstand low oxygen (hypoxia tolerance) is a polygenic and mechanistically conserved trait that has important implications for both human health and evolution. However, little is known about the diversity of genetic mechanisms involved in hypoxia adaptation in evolving populations. We used experimental evolution and whole-genome sequencing in Drosophila melanogaster to investigate the role of...

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Identifiers

PMID: 26576852
DOI: 10.1093/molbev/msv248
PMCID: PMC4866538

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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