Article
Physiological Genomics of Adaptation to High-Altitude Hypoxia.
Annual review of animal biosciences - 16 Feb 2021
Storz Jay F, Cheviron Zachary A
Abstract excerpt
Population genomic studies of humans and other animals at high altitude have generated many hypotheses about the genes and pathways that may have contributed to hypoxia adaptation. Future advances require experimental tests of such hypotheses to identify causal mechanisms. Studies to date illustrate the challenge of moving from lists of candidate genes to the identification of phenotypic targets of selection, as...
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