Article
Prokineticins in central and peripheral control of human reproduction.
Hormone molecular biology and clinical investigation - 1 Nov 2015
Traboulsi Wael, Brouillet Sophie, Sergent Frederic, Boufettal Houssine, Samouh Naima, Aboussaouira Touria, Hoffmann Pascale, Feige Jean Jacques, Benharouga Mohamed, Alfaidy Nadia
Abstract excerpt
Prokineticin 1 (PROK1) and (PROK2), are two closely related proteins that were identified as the mammalian homologs of their two amphibian homologs, mamba intestinal toxin (MIT-1) and Bv8. PROKs activate two G-protein linked receptors (prokineticin receptor 1 and 2, PROKR1 and PROKR2). Both PROK1 and PROK2 have been found to regulate a stunning array of biological functions. In particular, PROKs stimulate...
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