Article
Interactome analysis of gene expression profile reveals potential novel key transcriptional regulators of skin pathology in vitiligo.
Genes and immunity - 1 Jan 2000
Dey-Rao R, Sinha A A
Abstract excerpt
Selective destruction of epidermal melanocytes is central to vitiligo (VL), a common acquired, autoimmune depigmentory disorder of the skin. Like other autoimmune diseases, the pathogenesis of VL is obscure and both multifactorial and polygenic. The prevailing theory is that VL may be part of an autoimmune diathesis. To evaluate mechanisms underlying disease development and progression, we studied genome-wide...
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