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Integrative Genetics and Multiomics Analysis Unveil Mechanisms and Therapeutic Targets in Vitiligo: Insights from GWAS-meta, Microarray, Single-cell Transcriptomics, and ChIP-seq Data, Highlighting JAK/STAT Pathway Regulation of CTSS in Vitiligo

2024-09-08

Abstract excerpt

<title>Abstract</title> <p>Background: Vitiligo is a complex autoimmune disease characterized by the loss of melanocytes, leading to skin depigmentation. Despite advances in understanding its genetic and molecular basis, the precise mechanisms driving vitiligo remain elusive. Integrating multiple layers of omics data can provide a comprehensive view of disease pathogenesis and identify potential therapeutic targ...

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Literature Corpus work: 5929b35e-c31b-5e6d-998c-fd8338058c29
DOI: 10.21203/rs.3.rs-4775414/v1

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