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Article

Dissecting age-specific genetic architecture of vitiligo through integrative Post-GWAS analysis.

Frontiers in immunology - 1 Jan 2026

Si Qingqing, Wang Shenglan, Chen Junru, Feng Yuanyu, Zhao Ruike, Sun Dongjie

Abstract excerpt

Background: Vitiligo is a chronic acquired depigmentation disorder with a global prevalence of 0.5-2%. Early-onset (EO) and late-onset (LO) subtypes exhibit marked differences in clinical presentation and disease progression, yet their genetic underpinnings have not been fully elucidated. Methods: We employed linkage disequilibrium score regression (LDSC) to quantify genetic correlation between EO and LO...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42183231
DOI: 10.3389/fimmu.2026.1783791
PMCID: PMC13194528

Genes

GZMB
RNASET2
TEF

Provenance

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