Article
The Genetic Basis of Vitiligo.
The Journal of investigative dermatology - 1 Feb 2021
Spritz Richard A, Santorico Stephanie A
Abstract excerpt
Vitiligo is a complex disease in which autoimmune destruction of epidermal melanocytes results in patches of depigmented white skin. Vitiligo has an estimated prevalence of about 0.2-2% in different populations and approximately 0.4% in the European-derived white (EUR) population. The fraction of disease risk attributable to genetic variation, termed heritability, is high, with estimates from family studies in...
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