Article

Melanocyte loss dominates the vitiligo transcriptome: a rank-based meta-analysis

2026-02-09

Abstract excerpt

Vitiligo is an autoimmune disorder characterized by the destruction of melanocytes. We performed a rank-based meta-analysis of six independent transcriptomic studies (115 samples) spanning microarray, bulk, and single-cell RNA-seq platforms to identify consensus signatures of lesional skin. Robust rank aggregation identified 108 downregulated and 6 upregulated genes. Pathway analysis revealed consistent suppressio...

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Literature Corpus work: 73a5e252-c2f9-5257-82e6-03cd66ee4546
DOI: 10.64898/2026.02.07.26345817

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