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Article

Common Polymorphisms That Affect Folate Transport or Metabolism Modify the Effect of the MTHFR 677C > T Polymorphism on Folate Status.

The Journal of nutrition - 1 Jan 2016

Bueno Olalla, Molloy Anne M, Fernandez-Ballart Joan D, García-Minguillán Carlos J, Ceruelo Santiago, Ríos Lídia, Ueland Per M, Meyer Klaus, Murphy Michelle M

Abstract excerpt

BACKGROUND: Although combinations of biologically relevant polymorphic variants affect folate status, most studies have focused on the effects of individual polymorphisms; however, these effects may be altered by interactions between polymorphisms. OBJECTIVE: We investigated the individual and combined effects of polymorphisms that affect folate transport or metabolism on folate status. METHODS: The associations...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26561410
DOI: 10.3945/jn.115.223685

Genes

MTHFR
MTRR
MTHFD1
DHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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