Article
Prevalence and effects of gene-gene and gene-nutrient interactions on serum folate and serum total homocysteine concentrations in the United States: findings from the third National Health and Nutrition Examination Survey DNA Bank.
The American journal of clinical nutrition - 1 Jul 2008
Yang Quan-He, Botto Lorenzo D, Gallagher Margaret, Friedman J M, Sanders Christopher L, Koontz Deborah, Nikolova Stanimila, Erickson J David, Steinberg Karen
Abstract excerpt
BACKGROUND: Abnormalities of folate and homocysteine metabolism are associated with a number of pediatric and adult disorders. Folate intake and genetic polymorphisms encoding folate-metabolizing enzymes influence blood folate and homocysteine concentrations, but the effects and interactions of these factors have not been studied on a population-wide basis. OBJECTIVE: The objective was to assess the prevalence of...
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