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Article

MYC-induced reprogramming of glutamine catabolism supports optimal virus replication.

Nature communications - 12 Nov 2015

Thai Minh, Thaker Shivani K, Feng Jun, Du Yushen, Hu Hailiang, Ting Wu Ting, Graeber Thomas G, Braas Daniel, Christofk Heather R

Abstract excerpt

Viruses rewire host cell glucose and glutamine metabolism to meet the bioenergetic and biosynthetic demands of viral propagation. However, the mechanism by which viruses reprogram glutamine metabolism and the metabolic fate of glutamine during adenovirus infection have remained elusive. Here, we show MYC activation is necessary for adenovirus-induced upregulation of host cell glutamine utilization and increased...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26561297
DOI: 10.1038/ncomms9873
PMCID: PMC4660206

Genes

MYC
GLS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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