Article

Glycolytic Inhibitor 2-Deoxy-D-Glucose Attenuates SARS-CoV-2 Multiplication in Host Cells and Weakens the Infective Potential of Progeny Virions

2022-01-10

Abstract excerpt

The COVID-19 pandemic is an ongoing public health emergency of international concern. There is an emergent requirement to find potential therapeutics to effectively counter this fast mutating SARS-CoV-2 virus-induced pathogenicity. Virus-infected host cells switch their metabolism to a more glycolytic phenotype. This switch induced by the virus is needed for faster production of ATP and higher levels of anabolic i...

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Literature Corpus work: 7ca317e0-460f-5470-b215-715bd62e39ec
DOI: 10.2139/ssrn.3981554

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