Article
Glycolytic inhibitor 2-Deoxy-D-glucose attenuates SARS-CoV-2 multiplication in host cells and weakens the infective potential of progeny virions
2021-06-13
Abstract excerpt
The COVID-19 pandemic is an ongoing public health emergency of international concern. While a lot of efforts are being invested in vaccinating the population, there is also an emergent requirement to find potential therapeutics to effectively counter this fast mutating SARS-CoV-2 virus-induced pathogenicity. Virus-infected host cells switch their metabolism to a more glycolytic phenotype. This switch induced by th...
Topics
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- Animal Disease Management and Epidemiology
- Cytomegalovirus and herpesvirus research
- Diet, Metabolism, and Disease
- Herpesvirus Infections and Treatments
- Liver Disease Diagnosis and Treatment
- Metabolism, Diabetes, and Cancer
- Viral-associated cancers and disorders
- Viral gastroenteritis research and epidemiology
Identifiers and source
- Literature Corpus work
- d91d28c3-8f66-564b-9f70-b1dba0d44c81
- DOI
- 10.1101/2021.06.12.448175
