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Article

The C677T MTHFR genotypes influence the efficacy of B9 and B12 vitamins supplementation to lowering plasma total homocysteine in hemodialysis.

Journal of nephrology - 1 Oct 2016

Achour Ons, Elmtaoua Sahbi, Zellama Dorsaf, Omezzine Asma, Moussa Amira, Rejeb Jihene, Boumaiza Imene, Bouacida Lobna, Rejeb Nabila Ben, Achour Abdellatif, Bouslama Ali

Abstract excerpt

BACKGROUND: Hyperhomocysteinaemia, an independent risk factor for cardiovascular diseases, is common in hemodialysis patients (HD) and particularly in those homozygous for polymorphism of the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene. B vitamins supplementation has been shown to lower plasma total homocysteine (tHcy), but this has been contreversed in several groups. The aim of our study was to...

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Identifiers

PMID: 26559681
DOI: 10.1007/s40620-015-0235-8

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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