Article
[Methylenetetrahydrofolate reductase gene polymorphism and plasma homocysteine levels in hemodialysing patients].
Zhonghua nei ke za zhi - 1 Aug 2002
Yao Ying, Liu Huilan, Zhang Xiaojie, Duan Xiaofeng
Abstract excerpt
OBJECTIVE: To study the influence of mutation of 677 C to T in the methylenetetrahydrofolate reductase (MTHFR) gene on the plasma total homocysteine (tHcy) levels in hemodialysis patients. METHODS: The study population included 40 healthy subjects and 53 patients with end-stage renal disease (ESRD) undergoing hemodialysis. C 677 T transition in the MTHFR gene was detected by Hinf 1 restriction enzyme analysis....
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