Article
[Efficacy and safety of two vitamin supplement regimens on homocysteine levels in hemodialysis patients. Prospective, randomized clinical trial].
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia - 1 Jan 2005
Sánchez Alvarez J E, Pérez Tamajón L, Hernández D, Alvarez González A, Delgado P, Lorenzo V
Abstract excerpt
UNLABELLED: High levels of homocysteine (tHcy) are frecuent in MHD patients, and recognized as a risk factor for cardiovascular events. Vitamin supplements have been shown to lower serum Hcys, although optimal dose and efficacy is not well defined. Moreover, methylenetetrahydrofolate reductase (MTHFR) gene polymorphism can modulate its prevalence and response to treatment. OBJECTIVE: To evaluate efficacy and...
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