Article
Modulator effects of the methylenetetrahydrofolate reductase C677T polymorphism on response to vitamin B12 therapy and homocysteine metabolism.
DNA and cell biology - 1 May 2012
Sensoy Nazli, Şoysal Yasemin, Kahraman Ahmet, Doğan Nurhan, Imirzalioğlu Necat
Abstract excerpt
In this study, our aim was to investigate the association of methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism on the vitamin B12 therapy response in 95 patients with vitamin B12 deficiency and 92 healthy control subjects using vitamin B12, plasma total homocysteine (tHcy), and folat...
Topics
- Adult
- Case-Control Studies
- Female
- Folic Acid
- Genotype
- Homocysteine
- Humans
- Male
- Methylenetetrahydrofolate Reductase (NADPH2)
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Polymorphism, Restriction Fragment Length
- Vitamin B 12
- Vitamin B 12 Deficiency