Article
Comparative study of response to treatment with supraphysiologic doses of B-vitamins in hyperhomocysteinemic hemodialysis patients.
The Israel Medical Association journal : IMAJ - 1 Apr 2004
Nakhoul Farid, Abassi Zaid, Plawner Michal, Khankin Eli, Ramadan Rawi, Lanir Noami, Brenner Benjamine, Green Jacob
Abstract excerpt
BACKGROUND: Hyperhomocysteinemia is a well-recognized risk factor for accelerated atherosclerosis in hemodialysis patients. OBJECTIVES: To examine the effects of two doses of vitamins B6 and B12 and folic acid on homocysteine levels in hemodialysis patients and assess the functional impact of the methylenetetrahydrofolate reductase genotype on the response to treatment. METHODS: In a randomized prospective study,...
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