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Methylenetetrahydrofolate reductase genotype, vitamin B12, and folate influence plasma homocysteine in hemodialysis patients.

American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 May 2002

Nakamura Takamichi, Saionji Katsu, Hiejima Yoshimitsu, Hirayama Hideo, Tago Kiichiro, Takano Hajime, Tajiri Munemasa, Hayashi Katsuji, Kawabata Masaki, Funamizu Makiko, Makita Yoshio, Hata Akira

Abstract excerpt

Hyperhomocysteinemia, a well-recognized cardiovascular risk factor, is frequent in hemodialysis (HD) patients. A common polymorphism in the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene, C-->T substitution at nucleotide 677, is associated with homocysteine (Hcy) level elevation. We examin...

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Identifiers

PMID: 11979347
DOI: 10.1053/ajkd.2002.32779

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11979347-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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Methylenetetrahydrofolate reductase genotype, vitamin B12, and folate influence plasma homocysteine in hemodialysis patients.PMID 11979347Read ↗

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