Article
Effects of folic acid before and after vitamin B12 on plasma homocysteine concentrations in hemodialysis patients with known MTHFR genotypes.
Clinical chemistry - 1 Jan 2006
Pastore Anna, De Angelis Sandro, Casciani Stefania, Ruggia Rosalba, Di Giovamberardino Gianna, Noce Annalisa, Splendiani Giorgio, Cortese Claudio, Federici Giorgio, Dessi' Mariarita
Abstract excerpt
BACKGROUND: Treatment with folic acid and vitamin B12 appears to be effective in lowering total plasma homocysteine (tHcy) concentrations, but whether vitamin B12 alone lowers tHcy in patients with normal vitamin B12 status is unknown. The aims of the present study were to explore the effect of individual supplementation with folic acid or vitamin B12 on tHcy concentrations in hemodialysis (HD) patients and to...
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